Oleg glances furtively around him and, confident that nobody is watching, slips inside the entrance to a decaying Soviet-era block of flats, where Sasha is waiting for him. Ensconced in the dingy kitchen of one of the apartments, they empty the contents of a blue carrier bag that Oleg has brought with him — painkillers, iodine, lighter fluid, industrial cleaning oil, and an array of vials, syringes, and cooking implements.
History of Desomorphine. Desomorphine was first discovered and patented by a German team working for the pharmaceutical company Knoll around The drug was then synthesized in the U. It is a semi-synthetic opioid that is most closely related to morphine in chemical structure and it produces opioid-like effects, according to the Drug Enforcement Administration DEA.
Desomorphine has the molecular formula C 17 H 21 NO 2and molecular weight The salt forms of desomorphine dissolve easily in water.
The drug was never sold commercially in the U. Substances in the DEA Schedule I have no currently accepted medical use in the United States, a lack of accepted safety for use under medical supervision, and a high potential for abuse. However, desomorphine was used medically in Switzerland under the brand name Permonid as well as in Russia to treat severe pain.
The drug was manufactured by the pharmaceutical company Hoffman- Roche and was available in ampule and suppository forms. The drug stopped being manufactured commercially in but was still made until for one patient in Switzerland. The patient was suffering from an unspecified disease and had specific pain relief needs that required desomorphine.
According to reportsthe individual consumed 80 ampules of Permonid daily. Each ampule contained 2 mg of desomorphine, meaning they took mg of desomorphine per day.
However, abuse of homemade desomorphine was first reported in Siberia in when Russia started a major crackdown on heroin production and trafficking. This reaction is with codeine or prescription opioids like OxyCotin or Vicodin and thionyl chloride, which is a chemical found in batteries. Finally, the dihydrodesoxycodeine is demethylated to create desomorphine.
As desomorphine is a type of synthetic morphine it produces opiate-like effects, including pain relief and euphoria. The drug has a rapid onset and a short half-life. It affects only lasts between two and three hours.
Desomorphine is more potent than morphine, approximately 10 times more powerful than morphine. It was also found to be faster-acting and more effective than morphine for the rapid relief of severe pain. It has withdrawal symptoms similar to morphine and other opioids.
According to Diagnostic and Statistical Manual of Mental Disorders DSM—5 criteria, s and symptoms of opioid withdrawal include nausea, vomiting, diarrhea, muscle aches, insomnia, sweating, hyperthermia, among others. As for negative side effects, early studies showed that desomorphine caused respiratory depression, sedation, dizziness, nausea, vomiting, constipation, mental clouding, hypotension, and urinary retention.
Due to the more severe negative side effects at similar doses to morphine, it was abandoned for medical purposes. Its street names are Krokodil and Crocodil. Some believe the name comes from the fact that users often develop extreme skin sores, infections, and gangrene that take on a discolored green, grey, black scale-like appearance that resembles the skin of a crocodile.
Krokodil can also have other variations in spelling such as: Krocodil, Krocodyl, or Krok.
It has also been referred to as Alligator Drug and Zombie Drug. in. Log into your .
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